Cytotoxic Activity of Som Metal Oxides Nanoparticles against Cell line (MES-SA)

Abstract

Nano particles MgO and  Fe₂O₃ with moral crystallinity were prepared by simple chemical method.The structure and the size of the MgO and  Fe₂O₃ Nps were examined by SEM and XRD. Characterizations of the  nano-products were done using X-ray diffraction (XRD)which confirmed the crystal-like nature of  MgO and Fe₂O₃ NPs. More, field emission scanning electron microscope (FESEM) has been used to demonstrate the morphology of the nanostructures of MgO and Fe2O3 NPs. The data yielded the average grain size of  MgO,Fe₂O₃ NPs calculated by SEM and XRD(29, 26.02)nm and(6.529,14.569)nm respectively. Energy-dispersive X-ray spectroscopy (EDS) spectrum and XRD pattern recommended that prepared  MgO and Fe2O3 NPs were very pure. According to the MTT assay results of MES-SA cells the IC₅₀ (95.8, 112.9) μg/mL. invasive cell rate reduced to 64% of the control group for MgO NPs treatment, and to 89% of the control group for Fe2O3 NPs treatments.